Senior Scientist, Pharmacology Lead, Pharmacology / Toxicology

Senior Scientist, Pharmacology Lead, Pharmacology / Toxicology

Who We AreRampart Bioscience is an early-stage biotechnology company pioneering a new class of medicines for individuals, especially children, living with genetically driven diseases.Powered by its non-viral DNA delivery platform, Rampart’s mission is to develop transformative medicines that achieve higher standards for potency and safety than current gene therapies. Rampart is funded by several global, top-tier healthcare investment firms, and is led by seasoned experts in gene delivery, protein sciences, and clinical translation.When you join Rampart, you are not simply advancing your career. You are joining a team that is dedicated to realizing the potential of gene therapy to provide effective, safe, and long-lasting treatments for a wide range of diseases. We are mission-driven and guided by our values:· People first. Nothing shall be done to harm human dignity or get in the way of one’s freedom.· Unbound by convention. We embrace the unfamiliar and are willing to stand alone together.· Actions speak. We have a bias for action and serve with humility as we work to achieve new ground.· Relationships matter. We build authentic relationships founded on trust, integrity, diligence, and honor.· We care. We are disciplined and passionate. We love what we do, who we do it with, and who we do it for. As we advance our work in exciting ways, we are selectively hiring talented team members to join us in our Southern California locations. For more information, please visit www.rampartbio.com.

About the job

Rampart Bio is working on cutting-edge science to advance breakthrough treatments for rare diseases and is looking for a Senior Scientist to lead our in vivo pharmacology efforts. You will report directly to the Vice President of Research and be responsible for assessing the efficacy and safety of gene-based drug candidates. In addition, you will perform data analysis and interpretation, oversee risk assessment and regulatory compliance, and contribute toward collaborative research studies. You will also assist in the development of strategies for preclinical studies, regulatory submissions, and clinical trials. Key Responsibilities: · Lead the design, conduct and interpretation of nonclinical in vivo studies to support pharmacology, pharmacokinetics/biodistribution, and safety assessments.· Assist in selection and then lead procurement and development of appropriate animal models and assays to enable advancement of platform and pipeline programs.· Develop animal study protocols and schedule and monitor studies, both internal and external.· Develop and oversee biomarker assessments.· Write study reports for internal and regulatory purposes. · Oversee laboratory animal management and breeding as required.· Serve as pharmacology/toxicology representative in project team meetings.· Assist in building a strong preclinical team by training and supervising junior scientists, establishing practices that ensure successful study conduct, and expanding the department’s technical capabilities.

Qualifications/Requirements:· Ph.D. in a relevant scientific field.· 5+ years of experience in a pharmaceutical, biotechnology or related environment.· Experience in design, conduct, oversight, and interpretation of animal studies required.· Experience in animal model selection and development is required. · Strong scientific understanding of non-clinical in vivo pharmacology evaluation.· Good organizational and communication skills.· Independent, motivated, and ability to work with a sense of urgency.· Position located onsite in La Jolla, CA.· Ability to travel domestic and internationally when required. Compensation, Benefits & Additional Information

Senior Scientist: Compensation range: $105,000- $130,000 commensurate with experience and qualifications.

We are proud to provide a robust benefits package for our employees, including:

• Medical, dental and vision insurance for employees and their dependents, with a 90% - 100% company contribution.· Life, AD&D and disability insurance for employees, with a 100% company contribution.· 401(k).· Generous amounts of paid time off through our vacation, holiday, sick and floating time off programs including floating “beach” days and your birthday off.· Ability to participate in the company’s Stock Benefit Plan and annual Bonus Plan.

If you are interested in this position, please attach your cover letter with your resume in one document. In your cover letter, explain your qualifications and why you think you would be a fit for this position within Rampart Bio.

Actual compensation packages are based on a variety of factors that are unique to each candidate including, but not limited to: skill set, depth of experience, education, certifications, and specific work location.

Rampart Bioscience is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, disability, age, veteran status or any other applicable legally protected characteristics.